Education
Ph.D. in Neuroscience (2012)
University of Illinois at Urbana-Champaign
Advisor: Prof. Peter Yingxiao Wang
University of Illinois at Urbana-Champaign
Advisor: Prof. Peter Yingxiao Wang
M.S. in Pharmaceutical Science (2005)
Seoul National University College of Pharmacy
Advisor: Prof. Chong-Kook Kim
Seoul National University College of Pharmacy
Advisor: Prof. Chong-Kook Kim
B.S. in Pharmacy (2003)
Seoul National University College of Pharmacy
Seoul National University College of Pharmacy
Postdoctoral Research
Stanford University College of Medicine
Advisor: Prof. Michael Z. Lin
Advisor: Prof. Michael Z. Lin
University of Illinois at Urbana-Champaign
Advisor: Prof. Ning Wang
Advisor: Prof. Ning Wang
Professional Positions
Professor (2023 – Present)
Seoul National University College of Medicine
Department of Biological Sciences
Seoul National University College of Medicine
Department of Biological Sciences
Principal Investigator (2014 – 2023)
Korea Institute of Science and Technology (KIST)
Brain Science Institute
Korea Institute of Science and Technology (KIST)
Brain Science Institute
Selected Publications
Journal of Neuroscience (2025) Optogenetic control of dopamine receptor 2 reveals a novel aspect of dopaminergic neurotransmission in motor function, 45(1): e1473242024
Small Methods (2024) Novel FRET-based immunological synapse biosensor for the prediction of Chimeric Antigen Receptor-T cell function, 9(3): e2401016
Sensors and Actuators B: Chemical (2022) Combinatorial effects of RhoA and Cdc42 on the actin cytoskeleton revealed by photoswitchable GEFs, 369:132316
Acta Neuropathologica (2022) Decreased FAK activity and focal adhesion dynamics impair proper neurite formation of medium spiny neurons in Huntington’s disease, 144(3):521-536
Cell Reports (2022) Optical regulation of endogenous RhoA reveals switching of cellular responses by signal amplitude, 40(2):111080
Progress in Neurobiology (2022) Differential receptor crosstalk in the DRD1-DRD2 heterodimer upon phasic and tonic dopamine signals, 213:102266
Annual Review of Biochemistry (2021) Optobiochemistry: Genetically encoded optical control of protein activity by light, 90:475-501
Sensors (2021) Genetically encoded biosensors based on fluorescent proteins, 21(3), 795
Analytical Chemistry (2021) Spatiotemporal kinetics of GPCR activity and function during endosomal trafficking pathway, 93(4):2010-2017
ACS Sensors (2020) Visualization of autophagy progression by Red-Green-Blue autophagy sensor, 5(12):3850-3861
Nature Communications (2017) Engineered Proteins with Sensing and Activating Modules for Automated Reprogramming of Cellular Functions, 8(1):477
Nature Communications (2014) Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression, 5:4619
PNAS (2013) Distinct biophysical mechanisms of FAK mechanoactivation by different extracellular matrix proteins, 110(48):19372-7
Nature Communications (2013) N-cadherin regulates spatially polarized signals through distinct p120ctn and β-catenin-dependent signaling pathways, 4:1589
Nature Communications (2011) Detect FAK Activations at Membrane Microdomains by FRET, 2:406
Chemistry & Biology (2009) Visualization of Src activity at different compartments of the plasma membrane by FRET imaging, 16(1): 48-57
J Gene Med (2006) Polyethylenimine-based antisense oligodeoxynucleotides of IL-4 suppress the production of IL-4 in a murine model of airway inflammation, 8(3): 314-2