Feb 26, 2025
Dr. Hyunbin Kim has been selected as a 2025 Sejong Fellow!! Congratulations, Dr. Kim!!
Nov 12, 2024
Our paper “Optogenetic control of dopamine receptor 2 reveals a novel aspect of dopaminergic neurotransmission in motor function” is accepted in Journal of Neuroscience!
Sep 6, 2024
Our paper “Unveiling the Complexity of G Protein-Coupled Receptor Heteromers: Advances in Live Cell Imaging Technologies and Biochemical Methods” is accepted in Med-X!
Sep 4, 2024
Our paper “Novel FRET-based Immunological Synapse Biosensor for the Prediction of Chimeric Antigen Receptor-T cell Function” is accepted in Small Methods (IF = 10.7)!
This paper is [BRIC 한빛사논문]!
https://www.snu.ac.kr/research/highlights?md=v&bbsidx=150285
July 2024
BRL grant (기초연구실사업) “GPCR signaling laboratory” is awarded to Seong Lab (2024 Aug – 2027 July)!
May 2024
NRF grant (중견연구자사업) “Development of dopamine neurotransmission monitoring sensors and pharmacogenetic control system“ is awarded to Seong Lab (2024 May – 2029 Apr)!
Mar 1, 2024
The paper “Dextran sodium sulfate (DSS)-induced colitis is alleviated in mice after administration of flavone-derived NRF2-activating molecules” is published in Life Sciences (IF = 6.1)!
Jan 10, 2024
Our paper “Optical sensing and control of T cell signaling pathways” is accepted in Front Physiol (IF = 4.0)!
Jan 2024
SNU-Naver grant “Fundamental therapeutic strategy for immune-mediated diseases using engineered Tregs” is awarded to Seong Lab (2024 Jan – 2026 Dec)!
Sep 1, 2023
The NEW Seong Lab starts at Seoul National University College of Medicine (Department of Pharmacology).
Mar 10, 2023
The paper “Integration of reconfigurable microchannels into aligned three-dimensional neural networks for spatially controllable neuromodulation” is published in Science Advances (IF = 13.6)!
Apr 2023
NRF grand (바이오의료개발사업) “Development of multi-FRET-based screening and evaluation system for GPCR biased ligands” is awarded to Seong Lab (2023 Apr – 2024 Dec)!
Oct 14, 2022
Our paper “Editorial: Visualization of molecular dynamics in live cells by fluorescent protein-based biosensors” is accepted in Front Cell Dev Biol (IF = 6.082)!
Sep 13, 2022
Hyunbin and In Yeop‘s paper “Genetically encoded fluorescent biosensors for GPCR research” is accepted in Front Cell Dev Biol (IF = 6.082)!
July 2, 2022
Hyunjoo‘s paper “Combinatorial effects of RhoA and Cdc42 on the actin cytoskeleton revealed by photoswitchable GEFs.” is accepted in Sensors and Actuators B: Chemical (IF = 9.221, JCR = 2.3%)!
June 26, 2022
Haenim‘s paper “Decreased FAK activity and focal adhesion dynamics impair proper neurite formation of medium spiny neurons in Huntington’s disease.” is accepted in Acta Neuropathologica (IF = 17.088, JCR = 1.6 %)!
This paper is [BRIC 한빛사논문]!
https://www.kist.re.kr/ko/news/latest-research-results.do?mode=view&articleNo=8577
June 21, 2022
Jeongmin and Haenim‘s paper “Optical regulation of endogenous RhoA reveals switching of cellular responses by signal amplitude.” is accepted in Cell Reports (IF = 9.99)!
This paper is [BRIC 한빛사논문]!
May 23, 2022
Hyunbin was selected for the Young Scientist Program (YSP) in 2022 Korean Society for Biochemistry and Molecular Biology (KSBMB, 생화학분자생물학회), and received the best presentation award! Congrats!!
Mar 25, 2022
Hyunbin‘s paper “Differential receptor crosstalk in the DRD1-DRD2 heterodimer upon different dopamine levels” is accepted in Progress in Neurobiology (IF=11.68)! Link
This paper is introduced as [BRIC 한빛사논문]!
Oct 15 2021
Dr. Seong received a Research excellence award for young scientist (신진학술상) from the Korean Society of Applied Pharmacology. It is all thanks to great works from all the Seong Lab members!
Sep 10 2021
Hyunbin‘s research proposal is selected as an UST Young Scientist Research Program (2021 Sep – 2022 Aug). Congrats!!
Aug 24 2021
NRF grant (중견연구자사업) “Development of fluorescent sensors and optogenetic tools for study of autophagy in neurodegenerative disease” is awarded to Seong Lab (2021 Sep – 2024 Feb)!
We are recruiting passionate students or postdocs who want to contribute to this exciting project. If you want to learn more about this, please contact Dr. Seong (jseong@kist.re.kr).
June 24 2021
Our review paper “Optobiochemistry: Genetically encoded control of protein activity by light” is published in Annual Review of Biochemistry (IF=25.4, JCR=0.8%). Link
This paper is introduced as [BRIC 한빛사논문]!
May 30 2021
Heejung‘s review paper “Fluorescent protein-based autophagy biosensors” is accepted in Materials-Biomaterials and Molecular Imaging Materials for Biomedical Research.
Mar 3 2021
Dr. Seong is a guest editor in the Frontiers in Cell and Developmental Biology for special research topic as follows.
Submission is now open! Link
Jan 22, 2021
Hyunbin, Jeongmin, Dr. Chun, Haenim‘s review paper “Genetically encoded biosensors based on fluorescent proteins” is accepted in Sensors.
Jan 5, 2021
Hyunbin‘s paper “Spatiotemporal kinetics of GPCR activity and function during endosomal trafficking pathway” is published in Analytical Chemistry (IF=6.785).
Dec 25, 2020
The paper “RhoA GTPase phosphorylated at tyrosine 42 by Src kinase binds to β-catenin and contributes transcriptional regulation of vimentin upon Wnt3A” is published online in Redox Biology (IF=9.986).
Dec 2, 2020
Heejung‘s paper “Visualization of Autophagy Progression by Red-Green-Blue Autophagy Sensor” is published in ACS Sensors (IF=7.33, JCR=2.9%), and selected as a Cover article!
July, 2020
Samsung grant “FRET-based selection and fine-tuning of CAR-T cells” is awarded to Seong Lab (2020 Sep – 2023 Aug)! Link
We are recruiting passionate students or postdocs who want to contribute to this exciting project. If you want to learn more about this, please contact Dr. Seong (jseong@kist.re.kr).
Mar, 2020
Dr. Seong is promoted as a Principal Researcher at KIST.
Oct 29, 2019
Haenim‘s paper “Aβ modulates actin cytoskeleton via SHIP2-mediated phosphoinositide metabolism” was published in Scientific Reports (IF=4.3).
Dec, 2018
The paper “Matrix rigidity-dependent regulation of Ca2+ at plasma membrane microdomains by FAK visualized by fluorescence resonance energy transfer” is accepted in Advanced Science (IF=15.84, JCR=4.93%).
Mar, 2018
Seong Lab was introduced on the focus news in the homepage of Kyung Hee University.
Sep 7, 2017
The paper “Engineered Proteins with Sensing and Activating Modules for Automated Reprogramming of Cellular Functions” is published in Nature Communications (IF=12.12).
June, 2017
Seong Lab started “Brain functional mapping project” funded by National Research Foundation of Korea (NRF)!
We are recruiting passionate people who wants to contribute to this project. If you want to learn more about this, please contact Dr. Seong (jseong@kist.re.kr).
June 7, 2017
Our paper collaborated with Prof. Inn and Prof. Kim was accepted in Chemical Communications (IF=6.3).
April 1, 2017
Our paper “FRET-based visualization of PDGF Receptor Activation at Membrane Microdomains” was accepted in Scientific Reports (IF=4.3).
Mar 1, 2017 
KIST Young Fellow grant is awarded to Seong Lab
Dr. Seong was selected as a KIST Young Fellow for the research proposal titled “Development of optogenetic tools to sense and control neurotransmission in live neurons“.
June 13, 2016
Our review paper “Advanced Fluorescence Protein-Based Synapse-Detectors” was accepted in Frontiers in Synaptic Neuroscience.
Mar 1, 2016
Dr. Seong has been appointed as an Associate Professor in the Biological Chemistry Program, University of Science and Technology (UST).
Oct, 2015
Samsung grant“galaxyBRAIN” (with Dr. Jinhyun Kim) is awarded!
# We are seeking highly motivated graduate students or postdoctoral fellows with great interests in live-cell imaging, molecular/protein engineering, neuroscience, pharmacology.
In particular for the functional brain mapping project, “galaxyBRAIN” funded by Samsung, the researchers with experience in molecular/protein engineering will be very welcomed. If you are interested in a position, please contact Dr. Seong with your CV.
Sep 11, 2015
Dr. Seong has been appointed as a KHU-KIST professor (경희대-KIST 학연교수). Please contact Dr. Seong if you are interested in the graduate program at KHU-KIST. Link
Mar, 2015
Dr. Seong is promoted as a Senior Researcher at KIST.
Feb, 2015
The paper “Distinct mechanisms regulating mechanical force-induced Ca2+ signals at the plasma membrane and the ER in human MSCs” is published in eLife (IF=8.28).
Aug, 2014
The paper “Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression” is published in Nature Communications (IF=12.12).
Jan, 2014
Dr. Seong starts to work at Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.